Amsterdam Born Children and their Development


Phase 1 has shown that the following factors lead to a higher risk of miscarriage: a premature birth, a child with a low weight at birth, high levels of the thyroid-stimulating hormone (TSH), low folic acid intake, unfavourable fatty acid profile (i.e. more omega-6 fatty acid and less omega-3 fatty acid), and too much work-related stress. Stress and mood swings (e.g. depression and anxiety) are related to smoking during pregnancy, but not to pregnancy-induced hypertension or gestational diabetes.

In relation to pregnancy outcomes in the various ethnic groups in the Netherlands, we found that Surinamese, Antillean and Ghanean women more often have a preterm delivery and give birth to a child with a low birth weight compared with Dutch women. In addition there are ethnic differences in the gestational period where women enrol in prenatal care, start to take folic acid supplements and the functioning of the thyroid. It was found that the differences in pregnancy outcomes can at least partially be explained by the factors mentioned above, besides other well-known risk factors, such as smoking.

For an overview of the study’s results so far, please follow this link. If you would like to know more about the results of Phase 1, please click here to read the scientific publications.