Amsterdam Born Children and their Development
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Pregnancy

Phase 1 (the start of the ABCD study) refers to the period of pregnancy and birth. Between January 2003 and March 2004 all pregnant women living in Amsterdam (12,373) were invited to participate in the study at their first antenatal visit to their general practitioner, midwife or gynaecologist. All these women received a questionnaire. In addition, they were asked to donate blood for research purposes.

Questionnaire
The (pregnancy) questionnaire contained a broad range of questions about socio-demographic background (age, educational level, marital status, country of birth, etc.), lifestyle (e.g. use of alcohol, smoking, physical activity), nutrition (e.g. use of folic acid supplements, consumption of fish), and psychosocial conditions (e.g. work-related stress, depressive symptoms, pregnancy-related fears, fatigue, etc.). 8266 pregnant women have filled in the pregnancy questionnaire.

Blood samples
The mother’s blood was analysed for nutrition-related markers as well as for nutrients (e.g. vitamins and minerals) which are known to be related to pregnancy outcomes and child development. 4350 pregnant women have donated a blood sample.